FUT3 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-17979-60, E-AB-17979-120, E-AB-17979-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: FUT3

Target Synonym: Alpha-(1; 3/1; 4)-fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; CD174; FT3B; Fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase; Lewis blood group); Fucosyltransferase 3; Fucosyltransferase III; FucT III; FucT-III; FUT3; FUT3; Galactoside 3(4)-L-fucosyltransferase; LE; Les; Lewis FT

Research Areas: Cardiovascular

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P21217

Background: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1, 3)-fucosyltransferase and alpha(1, 4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Concentration: 1.08 mg/mL

Immunogen: Synthetic peptide of human FUT3

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only