FSBP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES9031-50, ES9031-100

Citations, Manuals and MSDS Available upon request.

Background: disease:Defects in RAD54B may be a cause of tumor formation. Homozygous mutations at highly conserved position of RAD54B were observed in human primary lymphoma and colon cancer. These findings suggest that some cancers arise through defects of the RAD54B function., function:Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group., similarity:Belongs to the SNF2/RAD54 helicase family., similarity:Contains 1 helicase ATP-binding domain., similarity:Contains 1 helicase C-terminal domain., subunit:Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect., tissue specificity:Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 110-190

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 32kD

Human Gene ID: 100861412

Human SWISS Prot NO: O95073

Subcellular Location: Nucleus

Research Use Only