pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays. pNP-ADPr can be used for the research of poly(ADP-ribose)polymerase (PARP) enzymes.

Product information

CAS Number: 939028-75-8

Molecular Weight: 696.41

Formula: C21H26N6O17P2

Chemical Name: [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(2R,3R,4R)-3,4,5-trihydroxy-1-(4-nitrophenoxy)-1-oxopentan-2-yl]oxy})phosphoryl)oxy]phosphonic acid

Smiles: NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(=O)(OP(O)(O)=O)O[C@H]([C@H](O)[C@H](O)CO)C(=O)OC2C=CC(=CC=2)[N+]([O-])=O)[C@@H](O)[C@H]1O

InChiKey: RCULIYXBWRLLMU-GFIYZJRMSA-N

InChi: InChI=1S/C21H26N6O17P2/c22-18-13-19(24-7-23-18)26(8-25-13)20-16(32)15(31)12(42-20)6-40-46(39,44-45(36,37)38)43-17(14(30)11(29)5-28)21(33)41-10-3-1-9(2-4-10)27(34)35/h1-4,7-8,11-12,14-17,20,28-32H,5-6H2,(H2,22,23,24)(H2,36,37,38)/t11-,12-,14-,15-,16-,17-,20-,46?/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays.

Products are for research use only. Not for human use.