QSER1 Polyclonal Antibody

Catalogue Numbers: BS60158-50, BS60158-100

Sizes: 50µl, 100µl

Alternative Name: Glutamine and serine-rich protein 1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q2KHR3

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: QSER1 (glutamine and serine-rich protein 1) is a 1,735 amino acid protein that is phosphorylated upon DNA damage, probably by Atm or ATR. A single nucleotide polymorphism (SNP) that is nearly equidistant between the genes QSER1 and PRRG4 on chromosome 11, at just under 20 kb from each, has been suspected of association with Parkinson disease. Existing as two alternatively spliced isoforms, the QSER1 gene is conserved in chimpanzee, canine, bovine, mouse, rat, chicken and zebrafish, and maps to human chromosome 11p13. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: QSER1 polyclonal antibody detects endogenous levels of QSER1 protein.

Bioworld Molecular Weight: ~ 190 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of QSER1 polyclonal antibody at 1:500 dilution
Lane 1: A549 whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: PC12 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human QSER1.

Conjugate: Unconjugated

Modification: Unmodified