PROC (light chain, Cleaved-Leu179) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20045-50, ES20045-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],

Alternate Name: Vitamin K-dependent protein C (EC 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide]

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 17 45kD

Human Gene ID: 5624

Human SWISS Prot NO: P04070

Subcellular Location: Secreted. Golgi apparatus. Endoplasmic reticulum.

Research Use Only