Eupalinolide H, a sesquiterpene lactone, has the potential to be used as natural anti-inflammatory agent.

Product information

CAS Number: 1402067-83-7

Molecular Weight: 420.45

Formula: C22H28O8

Chemical Name: (3aR, 4R, 9R, 11aR)-9-acetoxy-6-(hydroxymethyl)-10-methyl-3-methylene-2-oxo-2, 3, 3a, 4, 5, 8, 9, 11a-octahydrocyclodeca[b]furan-4-yl (2E)-4-hydroxy-2-methylbut-2-enoate

Smiles: CC(=O)O[C@@H]1CC=C(C[C@@H](OC(=O)/C(/C)=C/CO)[C@@H]2[C@@H](C=C1C)OC(=O)C2=C)CO |c:6,20|

InChiKey: INXZZSZBRLXKNT-HXFHGLJUSA-N

InChi: InChI=1S/C22H28O8/c1-12(7-8-23)21(26)29-19-10-16(11-24)5-6-17(28-15(4)25)13(2)9-18-20(19)14(3)22(27)30-18/h5,7,9,17-20,23-24H,3,6,8,10-11H2,1-2,4H3/b12-7+,13-9-,16-5+/t17-,18-,19-,20+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Eupalinolide H (2.5, 10, 40 μM) has significant inhibitory effects on IL-6 and TNF-α production in in RAW 264.7 cells.

Products are for research use only. Not for human use.