Anti-SARS-CoV Spike S1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-V1350-50, E-AB-V1350-100

Citations, Manuals and MSDS Available upon request.

Target Synonym: coronavirus s1; coronavirus spike; cov spike; ncov RBD; ncov s1; ncov spike; novel coronavirus RBD; novel coronavirus s1; ; novel coronavirus spike; RBD; S1; Spike RBD

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: SARS

Application: WB, ELISA

Isotype: IgG2a

Clonality: Monoclonal

Clone No.: 8

Background: The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.

Concentration: 1mg/mL

Immunogen: Recombinant SARS-CoV S1 Protein (His Tag)（Active）

Buffer: 0.2 μm filtered solution in PBS

Purification Method: Protein A Affinity

Dilution: WB 1:1000-1:5000 ELISA 1:1000-1:2000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only