LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.

Product information

CAS Number: 154446-98-7

Molecular Weight: 433.42

Formula: C19H23N5O7

Chemical Name: 2-{[5-(2-{2-amino-4-oxo-3H,4H,4aH,5H,6H,7H-pyrido[2,3-d]pyrimidin-6-yl}ethyl)furan-2-yl]formamido}pentanedioic acid

Smiles: NC1NC(=O)C2CC(CN=C2N=1)CCC1=CC=C(O1)C(=O)NC(CCC(O)=O)C(O)=O

InChiKey: FNQHSRGPACXGKI-UHFFFAOYSA-N

InChi: InChI=1S/C19H23N5O7/c20-19-23-15-11(16(27)24-19)7-9(8-21-15)1-2-10-3-5-13(31-10)17(28)22-12(18(29)30)4-6-14(25)26/h3,5,9,11-12H,1-2,4,6-8H2,(H,22,28)(H,25,26)(H,29,30)(H3,20,21,23,24,27)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

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