IKK-IN-3 is a potent and selective IkappaB kinase 2 (IKK2 or IKKβ) inhibitor, with IC50s of 19 and 400 nM for IKK2 and IKK1 (or IKKα), respectively.

Product information

CAS Number: 615528-53-5

Molecular Weight: 323.42

Formula: C17H17N5S

Chemical Name: N1-{12-methyl-4-phenyl-3-thia-1,7,10-triazatricyclo[7.3.0.0²,⁶]dodeca-2(6),4,7,9,11-pentaen-8-yl}ethane-1,2-diamine

Smiles: CC1=CN=C2C(NCCN)=NC3C=C(SC=3N21)C1C=CC=CC=1

InChiKey: AAFMUTYTWRBOGE-UHFFFAOYSA-N

InChi: InChI=1S/C17H17N5S/c1-11-10-20-16-15(19-8-7-18)21-13-9-14(23-17(13)22(11)16)12-5-3-2-4-6-12/h2-6,9-10H,7-8,18H2,1H3,(H,19,21)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.