GADD45A (6C3) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3059-50, MB3059-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P24522

Host: Mouse

Reactivity: Transfected

Applications: WB

All Applications: WB: 1/500-1/1000

Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of GADD45 alpha in CHO-K1Lysatesand CHO-K1 transfected by GADD45 alpha His fusion proteinLysates using GADD45 alpha antibody.

Bioworld Molecular Weight: Calculated MW: 18 kDa; Observed MW: 22 kDa

Specificity: IgG1

Alternative Name: DDIT1; GADD45

Immunogen: Purified recombinant human GADD45 α protein expressed in E.coli

Conjugate: Unconjugated

Modification: Unmodified