Jak3 (phospho-Tyr980/981) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES15392-50, ES15392-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],

Alternate Name: Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse

Immunogen: Synthesized phosho peptide around human Jak3 (Tyr980 and 981)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 125kD

Human Gene ID: 3718

Human SWISS Prot NO: P52333

Subcellular Location: Endomembrane system; Peripheral membrane protein. Cytoplasm.

Research Use Only