Cdc23 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1925-50, ES1925-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008],

Alternate Name: CDC23; ANAPC8; Cell division cycle protein 23 homolog; Anaphase-promoting complex subunit 8; APC8; Cyclosome subunit 8

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human APC8. AA range:251-300

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 69kD

Human Gene ID: 8697

Human SWISS Prot NO: Q9UJX2

Subcellular Location: intracellular, nucleoplasm, anaphase-promoting complex, cytosol,

Research Use Only