SHOX2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES13119-50, ES13119-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],

Source: Rabbit

Applications: WB; IHC; FCM

Dilution: WB 1:500-2000; IHC-p 1:50-300, FCM 1:100-200

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human SHOX2 AA range: 37-87

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 6474

Human SWISS Prot NO: O60902

Subcellular Location: Nucleus

Research Use Only