ARHGAP22 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6962-50, ES6962-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],

Alternate Name: ARHGAP22; RHOGAP2; Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human RHG22. AA range:565-614

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 77kD

Human Gene ID: 58504

Human SWISS Prot NO: Q7Z5H3

Subcellular Location: Cytoplasm. Nucleus. Mainly cytoplasmic. Some fraction is nuclear (By similarity).

Research Use Only