JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.

Product information

CAS Number: 1438284-00-4

Molecular Weight: 469.56

Formula: C23H27N5O4S

Chemical Name: 4-{5-methanesulfonyl-4H,5H,6H,7H-furo[3,2-c]pyridin-2-yl}-5-methyl-N-[4-(morpholin-4-yl)phenyl]pyrimidin-2-amine

Smiles: CC1=CN=C(NC2=CC=C(C=C2)N2CCOCC2)N=C1C1=CC2CN(CCC=2O1)S(C)(=O)=O

InChiKey: YDZHOVOPBMIATL-UHFFFAOYSA-N

InChi: InChI=1S/C23H27N5O4S/c1-16-14-24-23(25-18-3-5-19(6-4-18)27-9-11-31-12-10-27)26-22(16)21-13-17-15-28(33(2,29)30)8-7-20(17)32-21/h3-6,13-14H,7-12,15H2,1-2H3,(H,24,25,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

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