NKX6-1 Polyclonal Antibody

Catalogue Numbers: BS67240-50, BS67240-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P78426

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (By similarity).
Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 201% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of NKX6-1 protein.

Extra Notes: Western blot analysis of NKX6-1 expression in U87MG (A), mouse kidney (B), rat kidney (C), rat muscle (D) whole cell lysates.

Bioworld Molecular Weight: ~ 46 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: NKX6A; Homeobox protein Nkx-6.1; Homeobox protein NK-6 homolog A

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NKX6-1. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified