Anti-Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E/Envelope Protein Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-V1331-50, E-AB-V1331-100

Citations, Manuals and MSDS Available upon request.

Target Synonym: E; Envelope Protein

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Zika Virus

Application: WB, ELISA

Isotype: IgG1

Clonality: Monoclonal

Clone No.: 9

Background: Envelope of Zika virus is resposible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent to those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross reactivity with dengue and YF.Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.

Concentration: 1mg/mL

Immunogen: Recombinant ZIKV (strain Zika SPH2015) Envelope protein (Domain III, His Tag)

Buffer: 0.2 μm filtered solution in PBS

Purification Method: Protein A Affinity

Dilution: WB 1:1000-1:5000 ELISA 1:1000-1:2000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only