RALB Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11508-50, MB11508-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P11234

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles . Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells . Required for suppression of apoptosis (PubMed:17875936). In late stages of cytokinesis, upon completion of the bridge formation between dividing cells, mediates exocyst recruitment to the midbody to drive abscission (PubMed:18756269).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 23 kDa; Observed MW: 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of RALB in mouse colon lysates using RALB antibody., Western blot analysis of RALB in MCF-7 lysates using RALB antibody.

Alternative Name: Ras-related protein Ral-B

Immunogen: A synthetic peptide of human RALB

Conjugate: Unconjugated

Modification: Unmodified