K2-D3 10,000

delivers 10,000 IU of Vitamin D3 (as Cholecalciferol) and 45 mcg of Vitamin K2 (as Menaquinone-7 / MK-7) in a single vegetarian capsule, providing the highest-dose D3 and K2 combination in the XYMOGEN lineup for clients with documented Vitamin D deficiency, significant therapeutic D3 needs, limited sun exposure, malabsorption concerns, or elevated D3 requirements based on lab testing and practitioner guidance.

Vitamin D3 and Vitamin K2 are fat-soluble vitamins that function as a biological pair — D3 drives calcium absorption in the gut, and K2 directs where that absorbed calcium goes. Without adequate K2 to activate the calcium-directing proteins osteocalcin and Matrix Gla Protein (MGP), the calcium mobilized by high-dose D3 supplementation can deposit in arteries and soft tissue rather than reaching bone and teeth where it belongs. This calcium-directing function of K2 becomes increasingly important as D3 doses increase, making the pairing of 10,000 IU D3 with MK-7 at this dose a clinically considered combination that addresses both the therapeutic D3 need and the cardiovascular safety of calcium metabolism at higher D3 doses.

Cholecalciferol is the form of Vitamin D3 synthesized in human skin upon UVB exposure and is structurally identical to the D3 the body naturally produces from cholesterol and sunlight. This is the most bioavailable and clinically validated form of supplemental Vitamin D. At 10,000 IU (250 mcg), this is a high-therapeutic dose appropriate for correcting significant deficiency, supporting immune function in immune-compromised states, providing D3 support for those with fat malabsorption or obesity that reduces D3 bioavailability, and individuals in climates with minimal year-round sun exposure.

Menaquinone-7 (MK-7) is the long-chain, most bioavailable and bioactive form of K2, with a significantly longer half-life in circulation than shorter-chain forms such as MK-4. MK-7 remains active in the body for days rather than hours, providing sustained activation of K2-dependent proteins throughout the day from a single daily dose. At 45 mcg MK-7 per capsule, this formula provides meaningful K2 activity alongside the 10,000 IU D3 for cardiovascular calcium safety.

For clients with documented Vitamin D deficiency or those needing therapeutic D3 support: periodic Vitamin D lab testing (25-OH Vitamin D) is strongly recommended to guide dosing and ensure levels remain within the optimal range. Formulated to exclude wheat, gluten, yeast, soy protein, dairy, fish, shellfish, peanuts, tree nuts, egg, GMO-derived ingredients, artificial colors, artificial sweeteners, and artificial preservatives. NSF GMP-certified XYMOGEN professional formula. 60 vegetarian capsules.

10,000 IU per capsule is a high-potency therapeutic dose. Use under the guidance of a qualified healthcare practitioner with periodic Vitamin D lab monitoring. Not for general wellness use without practitioner guidance. Consult your healthcare professional before use if taking blood-thinning medications, as Vitamin K2 may interact with warfarin and anticoagulant therapy.

Key Benefits:

• Supports bone health through D3-driven calcium absorption and K2-directed calcium deposition in bone
• Supports cardiovascular health by directing calcium away from arteries via MK-7 activation of Matrix Gla Protein
• Supports healthy immune system function and immune cell regulation at therapeutic D3 levels
• Supports healthy mood, cognitive function, and neurological health via D3's neurological activity
• Supports healthy muscle function and strength
• Supports healthy blood pressure and cardiovascular regulation
• Corrects significant Vitamin D deficiency under practitioner guidance with lab monitoring
• MK-7 form of K2 provides the longest half-life and most sustained K2-dependent protein activation
• Cholecalciferol D3 identical to the form synthesized by human skin in sunlight
• One capsule daily simplicity at 10,000 IU therapeutic dose
• Formulated to exclude gluten, dairy, soy, GMOs, and artificial ingredients
• NSF GMP-certified XYMOGEN professional formula

What's Inside — Full Supplement Facts (per 1-capsule serving):

Vitamin D3 (as Cholecalciferol) — 250 mcg (10,000 IU) / 1,250% DV — Cholecalciferol is the natural form of Vitamin D3, structurally identical to the vitamin D synthesized in the skin upon UVB sunlight exposure. It is converted in the liver to 25-hydroxyvitamin D (the storage and testing form) and then in the kidneys and peripheral tissues to the active hormone 1,25-dihydroxyvitamin D (calcitriol). At 10,000 IU, this provides a high-therapeutic dose appropriate for correcting significant Vitamin D insufficiency or deficiency (serum 25-OH D below 30 ng/mL or significantly below 50 ng/mL), supporting immune function during illness or immunocompromised states, and maintaining adequate Vitamin D status in individuals with malabsorption, obesity, dark skin pigmentation, or extremely limited sun exposure. Vitamin D receptors are present in virtually every tissue in the body, and Vitamin D regulates hundreds of genes involved in immune function, inflammation, cell growth, neurology, and metabolism. Periodic 25-OH Vitamin D testing is essential to guide dosing at this level.

Vitamin K2 (as Menaquinone-7 / MK-7) — 45 mcg — Menaquinone-7 is the long-chain, naturally occurring form of Vitamin K2 found in fermented foods including natto (fermented soybeans, the richest dietary source), some aged cheeses, and certain fermented foods. MK-7 has a biological half-life of approximately 72 hours, significantly longer than MK-4 (which has a half-life of hours), meaning a single daily dose provides sustained, around-the-clock activation of the two critical K2-dependent proteins: osteocalcin (which incorporates calcium into bone matrix) and Matrix Gla Protein or MGP (which prevents calcium deposition in arterial walls). At higher D3 doses like 10,000 IU, the calcium mobilization effect of D3 is significant, making K2's calcium-directing activity particularly important for cardiovascular protection.

Other Ingredients: Microcrystalline cellulose, capsule (hypromellose and water), vegetable stearic acid, vegetable magnesium stearate, and silica. Vegetarian capsule.

Storage

Store in a cool, dry place. Keep out of reach of children.

Directions

Swallow 1 capsule daily with water, preferably at mealtime, or as directed by your healthcare professional. Taking with a fat-containing meal supports absorption of these fat-soluble vitamins.

Consult your healthcare professional prior to use. Individuals taking blood-thinning medication should discuss potential interactions with their healthcare professional. Consider total Vitamin K intake from food and supplements if taking anticoagulant medication. Periodic Vitamin D lab monitoring is recommended at this dose. Not for use without practitioner guidance. Do not use if tamper seal is damaged.

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XYMOGEN K2-D3 10,000 is a practitioner-trusted high-potency Vitamin D3 and K2 supplement available at SOLUDE Wellness & Beauty. It contains Vitamin D3 (as Cholecalciferol) 250 mcg (10,000 IU, 1,250% DV) and Vitamin K2 (as Menaquinone-7 / MK-7) 45 mcg per capsule, in a vegetarian hypromellose capsule with microcrystalline cellulose, vegetable stearic acid, vegetable magnesium stearate, and silica. It is designed to support bone health through D3-driven calcium absorption and K2-directed calcium deposition in bone, cardiovascular health through MK-7 activation of Matrix Gla Protein to prevent arterial calcium deposition, healthy immune function, mood and cognitive function, muscle function, and blood pressure. Appropriate for significant Vitamin D deficiency correction under practitioner guidance with periodic lab monitoring. Cholecalciferol D3 identical to skin-synthesized form. MK-7 provides longest-duration K2 activity from a single daily dose. High-potency 10,000 IU per capsule for therapeutic use. Formulated to exclude gluten, dairy, soy, GMOs, and artificial ingredients. NSF GMP-certified. 60 vegetarian capsules. One capsule daily with a fat-containing meal.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.