Rab 6A rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6964-50, ES6964-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],

Alternate Name: RAB6A; RAB6; Ras-related protein Rab-6A; Rab-6

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human RAB6A. AA range:113-162

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 24kD

Human Gene ID: 5870

Human SWISS Prot NO: P20340

Subcellular Location: Golgi apparatus membrane; Lipid-anchor. BICD2 facilitates its targeting to Golgi apparatus membrane.; [Isoform 1]: Golgi apparatus membrane; Lipid-anchor.; [Isoform 2]: Golgi apparatus membrane; Lipid-anchor.

Research Use Only