DMA trihydrochloride is a fluorescent compound (λex=340 nm, λem=478 nm).

Product information

CAS Number: 2095832-33-8

Molecular Weight: 577.93

Formula: C27H31Cl3N6O2

Chemical Name: 2-[2-(3,4-dimethoxyphenyl)-1H-1,3-benzodiazol-5-yl]-5-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazole trihydrochloride

Smiles: Cl.Cl.Cl.CN1CCN(CC1)C1C=C2N=C(NC2=CC=1)C1C=C2N=C(NC2=CC=1)C1C=C(OC)C(=CC=1)OC

InChiKey: NJYXXGULZHPSHV-UHFFFAOYSA-N

InChi: InChI=1S/C27H28N6O2.3ClH/c1-32-10-12-33(13-11-32)19-6-8-21-23(16-19)31-26(29-21)17-4-7-20-22(14-17)30-27(28-20)18-5-9-24(34-2)25(15-18)35-3;;;/h4-9,14-16H,10-13H2,1-3H3,(H,28,30)(H,29,31);3*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 15.9 mg/mL (27.51 mM; Need ultrasonic and warming).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The newly synthesized bisbenzimidazole derivatives DMA (6c) is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87) in comparison to Hoechst. In case of MCF7, the IC50 is observed at 5.3 μM for DMA. The IC50 determined in the case of HeLa is 3.4 μM for DMA.

Products are for research use only. Not for human use.